Antioxidant, Antidiabetic and Lipid Profiling of Spermadicyton Suaveolens in Streptozotocin (STZ) Induced Diabetic Rats

نویسندگان

چکیده

Diabetes is a life-threatening disease, and currently available synthetic medicines for treating diabetes are associated with various side effects. Therefore, there an unmet need to develop herbal remedies against as alternative medicines. Although local healers use the roots of Spermadicyton suaveolens (SS) manage diabetes, negligible research validate its antidiabetic properties. The present investigation aims assess antioxidant, antidiabetic, antihyperlipidemic potential ethanolic extract S. Suaveolen’s (EESS) on streptozotocin (STZ) induced diabetic rats. was screened in vitro antioxidant activity. vivo EESS (at 200 400 mg/kg) studied STZ-induced rats 20 days. displayed significant (p<0.05) administration mg/kg significantly reduced hyperglycemia, restored enzymes lipid profile-a high density lipoprotein (HDL) increased by single dose streptozotocin. Thus, could be promising medicine treatment hyperlipidemia.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

In vivo Antidiabetic and Antioxidant Potential of Stephania hernandifolia in Streptozotocin-Induced-Diabetic Rats

Stephania hernandifolia (Menispermaceae) is a medicinal plant, used by herbalists for treating various diseases, one of which is diabetes mellitus, in Darjeeling. However, its antidiabetic activity has not been scientifically investigated so far. The aim of this study, therefore, is to investigate the antidiabetic and antioxidant potential of the powdered corm of Stephania hernandifolia. This w...

متن کامل

Antidiabetic and Antioxidant Properties of Triticum aestivum in Streptozotocin-Induced Diabetic Rats

The antidiabetic and antioxidant potential of Triticum aestivum were evaluated by using in vivo methods in normal and streptozotocin-induced diabetic rats. Diabetes was induced in the Wistar strain albino rats by injecting streptozotocin at a dose of 55 mg/kg body weight. Ethanolic extracts of Triticum aestivum at doses of 100 mg/kg body weight were administered orally for 30 days. Various para...

متن کامل

Computation of In Vivo Antidiabetic Activity of Holarrhena Antidysenterica Seeds Extracts in Streptozotocin-Induced Diabetic Rats

Medicinal plants have curative properties due to the presence of various complex chemical compositions, which are found as secondary plant metabolites in one or more parts of the plant. The aim of this study was to compute the antidiabetic activity of Holarrhena antidysenterica   seeds extract in streptozotocin-induced diabetic rats. The experimental protocol designed as animals were divided i...

متن کامل

Antidiabetic Effect of Mallotus Philippinensis in Streptozotocin Induced Diabetic Rats

In the present work the antidiabetic activity of the Mallotus philippinensis was evaluated. The hydroethanolic bark extract showed significant increase in the levels of body weight, insulin and significant decrease in blood glucose, and glycosylated haemoglobin when administered orally for 30 days to STZ induced diabetic rats at a dose of 200 and 400mg/kg body weight. Phytochemical studies also...

متن کامل

Evaluation of Antidiabetic Activity of Cassia Glauca Lam. Leaf in Streptozotocin Induced Diabetic Rats

Normal 0 false false false MicrosoftInternetExplorer4 /* Style Definitions */ table.MsoNormalTable {mso-style-name:&quot;Table Normal&quot;; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-parent:&quot;&quot;; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0c...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Brazilian Journal of Pharmaceutical Sciences

سال: 2023

ISSN: ['2175-9790', '1984-8250']

DOI: https://doi.org/10.1590/s2175-97902023e21820